Left: OSU sophomore defensive end Joey Bosa reacts after a sack against Minnesota on Nov. 15 in Minneapolis. OSU won, 31-24.Credit: Mark Batke / Photo editorRight: Indiana junior running back Tevin Coleman carries the ball against North Texas on Oct. 4 in Bloomington, Ind. Indiana won, 49-24.Credit: Rachel Meert / Indiana Daily StudentA Heisman candidate, a Lombardi Award finalist and a jump in the College Football Playoff rankings are all topics surrounding the Ohio State football team.Coach Urban Meyer, however, is only focused on one thing.“I’m just worried about Indiana,” Meyer said Monday.The Hoosiers (3-7, 0-6) are scheduled to enter Columbus on Saturday as the only team in the Big Ten without a conference win, despite boasting the third-best rushing attack in the league.Leading the way for Indiana is junior running back Tevin Coleman, who has rushed for 1,678 yards and 12 scores in just 10 games for the Hoosiers.Coleman, a Doak Walker Award semifinalist, did not play last year against the Buckeyes due to injury as OSU cruised to a 42-14 win.Despite the easy victory, Meyer said Coleman is a “ridiculous” running back and compared him to other skilled running backs in the Big Ten.“The game he just played, (he had) 300 yards. You give him a crack, he has great acceleration, (he is) big, a little bit like the kid from Wisconsin. Just a big back,” Meyer said, referencing Wisconsin redshirt-junior running back Melvin Gordon in comparison to Coleman. “Those are all outstanding backs that will be playing on Sundays and this kid is one of those too.”Junior defensive lineman Adolphus Washington, who has started all but one game this season said it would not be acceptable to give up a big game to Coleman, even if the Buckeyes win.“Our goal is to keep him under 100 yards,” Washington said Wednesday. “That’s our goal and we are going to do that and still get the win.”Coleman’s carries are likely because of the season-ending injury suffered by Indiana junior quarterback Nate Sudfeld, who was averaging 191.8 passing yards per game before suffering the shoulder injury in a 45-29 loss to Iowa.Indiana has not won a game since Sudfeld’s injury and his replacement, freshman Zander Diamont, has thrown for just 282 yards in the four games he’s played.With a rush heavy offense, Washington said getting off blocks has been stressed in practice this week in order to shut down the Indiana rushing attack.“We know that these guys can run through arm tackles, so we have to work on getting off blocks every play,” he said. “Not trying to walk away from blocks and that kind of stuff because these backs are pretty good.”Sophomore Joey Bosa, who was named a finalist for the Lombardi Award on Thursday, added that it is not just Coleman, but the Hoosier offense as a whole that he is worried about.“Definitely (Coleman) and (the Hoosiers) are very fast-paced zone team,” Bosa said Wednesday. “They will be going side-to-side a lot and really up-tempo so just have to get in good shape this week.”Bosa, who enters Saturday’s game with a Big Ten best 11.5 sacks, said he has adjusted his personal goals from the beginning of the season because of his recent success.“I was actually going for 12, but now I am trying to beat the record,” he said. “(It would mean) a lot. As a sophomore, I think that would be something great to accomplish.”The current school record is 14 sacks held by Vernon Gholston, who set the mark during the 2007-08 season.Bosa’s single game high in sacks in his short Buckeye career is 2.5 in games against Penn State this season and against Illinois in 2013.If breaking the school record wasn’t incentive enough, Bosa said beating Indiana and getting a spot in the 2014 Big Ten Championship game should be.“That’s enough motivation right there, clinch the Big Ten (Championship game),” he said. “Every game is a big game obviously. We go in with the same mindset so there is just another step.”On the offensive side of the ball, the Buckeyes have a chance to break a few records of their own.Redshirt-freshman J.T. Barrett is just two passing touchdowns away from breaking former OSU quarterback Troy Smith’s school record of passing scores in a single season.In addition, sophomore running back Ezekiel Elliott has the opportunity to become the second player ever under Meyer to rush for 1,000 yards in a season, something Elliott said he doesn’t take for granted.“It means a lot. It’s something you dream of when you are a kid, being a football player at a Division I college,” Elliott said Wednesday. “Being able to rush for 1,000 yards, that’s just a great accomplishment.”Elliott currently sits at 954 yards rushing on the season, averaging 95.4 per game.Despite his rushing yards, Elliott said he believes he can do more than just run the football effectively.“I think I am just a versatile back. I can do a lot of things,” he said. “I take a lot of pride in my blocking, catching the ball out of the backfield, I can run it inside and outside.”Meyer said earlier in the week that he thought the Big Ten had some of the best running backs in the country and added “I’ve got to throw my guy in there,” when discussing including Elliott in that mix.Being mentioned by Meyer in such a light was motivating, Elliott said.“You just have to be thankful, thankful to God for the opportunities,” Elliott said. “Just have to go out there and keep grinding and get better every week.”Meyer also endorsed Barrett, whom Meyer said now belongs in the Heisman discussion heading into the Buckeyes’ matchup with Indiana.“I don’t know if my endorsement matters, but I (have) been fortunate to coach some guys that have been in New York, and he’s a Heisman candidate,” Meyer said Monday.Barrett acknowledged that the added attention has been “crazy” but said his focus is on one thing.“Being 1-0 at the end of the week, making sure that is the main focus,” Barrett said. “Not thinking about the Big Ten Championship Game, not thinking about that team up north, but just beat Indiana. That is the objective this week.”The Buckeyes and Hoosiers are scheduled to go head-to-head Saturday at Ohio Stadium. Kickoff is set for noon.
Joaquin Caparros has hailed the efforts of his side as Sevilla secured themselves a place in Europe for the 14th time for the past 15 yearsLas Sevillistas defeated Alaves 1-0 on the final day of La Liga due to a Wissam Ben Yedder goal to secure themselves seventh place and the final remaining qualification spot for Europe.After dismissing Vincenzo Montella at the end of April, Sevilla was in danger of failing to secure themselves a place for next season’s Europa League with the club having failed to win in nine matches at the time.The board turned to former coach Caparros, after 13 years away, and in his four games in charge, they won 10 points.“In this period we have shown that with great talent and a high dosage of the union, work and confidence you can achieve any goal,” Caparros wrote on Twitter.“Everything has been for you, those who are the basis of any shield and make this sport unmatched.Zidane reveals Sergio Ramos injury concern for Real Madrid Andrew Smyth – September 14, 2019 Zinedine Zidane has put Sergio Ramos’ availability for Real Madrid’s trip to Sevilla next weekend in doubt after withdrawing him against Levante.“How great it is to be a sevillista!En este periodo hemos demostrado que con un gran talento y una alta dosis de unión, trabajo y confianza se puede lograr cualquier objetivo.Todo ha sido por vosotros, los que sois la base de cualquier escudo y hacéis inigualable este deporte.¡Que grande es ser sevillista! pic.twitter.com/5oLFNhbRKy— Joaquín Caparrós (@JoaquinCaparros) May 20, 2018
Bournemouth manager Eddie Howe confirms Junior Stanislas is back in training and will soon return to action.Stanislas, however, won’t be available for selection when Leicester visit on Saturday. Eddie Howe also gave updates on the fitness of Ryan Fraser and Charlie Daniels is unavailable.The winger signed a contract extension until 2021 but has been injured with a knee injury since March.“During the international break, one of the big positives for us was that Junior joined in training and did really well.” How told Sky Sports.Brad Smith is loving his time at MLS Manuel R. Medina – August 27, 2019 Smith has been loaned from AFC Bournemouth to Seattle Sounders for a whole season, and the Australian footballer is enjoying his time there.“We did a maximal test during that break and he came first in that, so that was a really good sign, and shows he has done his rehabilitation with the best possible attitude.“He won’t be available for this game but is making the right progress.“Ryan Fraser had a hamstring problem (while on international duty), so he has been with the physios.“Charlie has had a niggle. He picked up a knee problem and we haven’t seen him during the international break.”
Bayern Munich will be without Thiago Alcantara for the next several weeks due to an ankle injuryThe Spanish midfielder sustained the damage to his ankle in Bayern’s 2-1 DFB-Pokal win over SV Roedinghausen on Tuesday.Thiago was replaced by Serge Gnabry in the 75th minute and received treatment on the sidelines afterwards for his injured ankle.Manager Niko Kovac admitted afterwards that he was facing an anxious wait for further updates on Thiago.“Thiago faces several weeks on the sidelines,” read a statement on the club website.Merson believes Arsenal should sign Sancho Manuel R. Medina – September 14, 2019 Borussia Dortmund winger Jadon Sancho might be the perfect player to play for the Gunners, according to former England international Paul Merson.“The Spain international tore the lateral collateral ligament and the articular capsule in his right ankle in the DFB Cup tie against the Regional League side SV Rödinghausen (2-1).“That was the diagnosis by the club doctor Dr. Hans-Wilhelm Müller-Wohlfahrt on Wednesday after returning from Osnabrück.”Corentin Tolisso and Kingsley Coman are the other players currently sidelined for Bayern.The Bavarians will next face SC Freiburg in a Bundesliga match this Saturday.
Liverpool legend Steve McManaman believes their Premier League title hopes could be left in jeopardy if Virgil van Dijk and Mohamed Salah got injuredThe Reds now lead by nine points from Tottenham, who lost 3-1 to Wolves, following Saturday’s 5-1 thrashing of Arsenal.Defending champions Manchester City are a further point behind in third, albeit with a game in hand against Southampton later today.Pep Guardiola’s side have endured a difficult month with injuries to some key players along with three defeats in their last four matches.And McManaman fears that Liverpool may find themselves in a similar struggle if they were to lose some of their own key men.“If Liverpool get a bad injury to Van Dijk or to Salah, at the same time, your thoughts start to change,” McManaman told BT Sport, via the Express.“Football is one of those things. When they say you have to take it game-by-game, that’s what you have to do. You have to hope everyone stays fit and the best team will win.“Of course Liverpool are absolutely flying at the moment but I’d still say Manchester City have got that little bit of an edge.Liverpool legend Nicol slams Harry Maguire’s Man United form Andrew Smyth – September 14, 2019 Steve Nicol believes Harry Maguire has made some “horrendous mistakes” recently, and has failed to find his best form since joining Manchester United.“They have got them at home next and they have won the league before.”The ex-Real Madrid midfielder is wary of placing too much expectation on the high-flying Reds.He added: “I don’t want to put too much pressure on Liverpool. Of course I want Liverpool to win the league, it goes without saying.“They are frightening at this moment but every year we pick out teams to win the elague, to not win the league, and you fall flat on your face three months later.“If it’s in April and they’ve got that much point difference, I’m quite happy to shout it from the rooftops but they’ve got a long way to go.”Although second-place Spurs don’t stand a chance due to their lack of squad depth.“No disrespect to Tottenham, I never thought they were in it,” said McManaman.“I always thought that their lack of depth in the squad would count against them.”
Credit: Ben Mills via Wikimedia Commons Humans have been consuming beverages that make them tipsy, drunk and/or sick for a very long time, of that there is little doubt. But why do we have the ability to metabolize ethanol in the first place? That’s what the team set out to answer. They began by sequencing an enzyme called ADH4—it’s what’s responsible for allowing us to metabolize ethanol. Other primates have it as well, but not all metabolize ethanol as well as we do. By sequencing ADH4 found in a 28 mammal species including 17 that were primates, the team was able to create a family tree of sorts based on ethanol metabolizing ability. The team then tested those sequences for their metabolizing ability by synthesizing nine kinds of the ADH4 enzyme. Doing so showed the researchers that most early primates had very little ability to metabolize ethanol for most of their early history.Then, about 10 million years ago, some of the ancestors of modern humans suddenly were able to do a much better job of it, while others that diverged and led to apes such as orangutans, did not. This discovery led the team to wonder what might have occurred to cause this to come about. They note that other evidence has shown that around this same time, the planet cooled slightly, making life a little more difficult for our tree dwelling ancestors. They suggest they began climbing down out of the trees to eat the fruit that fell, which gave them a food advantage and a reason for developing the ability to metabolize ethanol—otherwise they would have become too drunk from eating the fermenting fruit to defend themselves or live otherwise normal lives. If true, the theory would also offer a major clue as to why our ancestors became terrestrial. Study unlocks secret of how fruit flies choose fruit with just the right amount of ethanol (Phys.org)—A team of researchers in the U.S. has found evidence to support the notion that our pre-human ancestors were able to metabolize ethanol long before our later ancestors learned to take advantage of fermentation—to create alcoholic beverages. In their paper published in Proceedings of the National Academy of Sciences, the team describes how they genetically sequenced proteins from modern primates and used what they found to work backwards to discover just how long ago our ancestors have been able to metabolize ethanol. Journal information: Proceedings of the National Academy of Sciences Explore further © 2014 Phys.org Citation: Study shows pre-human ancestors adapted to metabolize ethanol long before humans learned about fermentation (2014, December 2) retrieved 18 August 2019 from https://phys.org/news/2014-12-pre-human-ancestors-metabolize-ethanol-humans.html More information: Hominids adapted to metabolize ethanol long before human-directed fermentation, PNAS, Matthew A. Carrigan, DOI: 10.1073/pnas.1404167111AbstractPaleogenetics is an emerging field that resurrects ancestral proteins from now-extinct organisms to test, in the laboratory, models of protein function based on natural history and Darwinian evolution. Here, we resurrect digestive alcohol dehydrogenases (ADH4) from our primate ancestors to explore the history of primate–ethanol interactions. The evolving catalytic properties of these resurrected enzymes show that our ape ancestors gained a digestive dehydrogenase enzyme capable of metabolizing ethanol near the time that they began using the forest floor, about 10 million y ago. The ADH4 enzyme in our more ancient and arboreal ancestors did not efficiently oxidize ethanol. This change suggests that exposure to dietary sources of ethanol increased in hominids during the early stages of our adaptation to a terrestrial lifestyle. Because fruit collected from the forest floor is expected to contain higher concentrations of fermenting yeast and ethanol than similar fruits hanging on trees, this transition may also be the first time our ancestors were exposed to (and adapted to) substantial amounts of dietary ethanol This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Kolkata: Here’s a caution to those who talk on the cellphone while driving, flouting orders of the Kolkata Police. The city police have put up billboards to create awareness among drivers not to use mobile phones while driving as part of the Safe Drive Save Life programme. Despite such notices, drivers — both owners and professionals — continue to talk on mobile phones while driving.To curb this “unethical” practice, the city police has requested people to take photos of those who talk while driving and send it to the Facebook page of the Kolkata Police so that the errant drivers can be booked. Also Read – Heavy rain hits traffic, flightsIt may be recalled that both city and state police took elaborate steps to stop the malice of talking while driving after a bus plunged into a canal in Murshidabad after breaking the railings of Balirghat bridge under Daulatabad police station on January 30. It was learnt that the driver of the ill-fated bus was talking over the phone when the accident took place and refused to pay heed to the passengers who requested him not to talk over the phone while driving. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedChief Minister Mamata Banerjee who had gone to oversee the rescue operations asked the police to take stringent measures against those who talk over the phone while driving.A senior police officer said despite repeated requests, some car and two-wheeler drivers have refused to listen to the police and continue to talk over the phone while driving. It is detrimental to the driver as well as to the pedestrians and drivers of other vehicles. Because the driver is busy talking, his mind is somewhere else and he also cannot hear any sound around him. “The new step is likely to be effective as pedestrians and passengers of other vehicles have been asked to cooperate with the police to put an end to this ‘unhealthy’ culture.”